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One major problem is, then, that weak or moderate modulation of transcripts present in a subpopulation of cells in an organ may become undetectable [10, 11].
In clusters 3 and 4, C. burnetii induced a moderate modulation of 18 and 24 genes, respectively (Fig. 3B).
We evidence moderate modulation of NCR ligands in colon carcinoma cells upon infection with H-1PV.
Isoflavones, a potent proteasome inhibitor [ 30], produced moderate modulation of steroid hormones and stabilization or reduction of serum prostate-specific antigen and reduced percentage of cells expressing Ki-67 posttreatment [ 31, 32] with no toxicity [ 33].
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Thus, the only moderate modulation after 6 h of pathogen stimulation as observed here is conceivably a conservative estimate of the actual priming-related changes.
A more likely reason for weak load EEG effects could be the moderate load modulation of only five letters as used in our study.
The impedance of the outer layer is characteristic for diffusion in a finite length region, coupled with an ion accumulation hindered kinetics at the inner/outer layer boundary at moderate frequencies, and modulation of the outer layer thickness at very low frequencies.
An AE activity with amplitude even as low as ~ 100 nT (in an otherwise quiet condition) has been found to cause penetration electric fields at equatorial region in the form of EEJ modulation of moderate degree, (10 20 nT), and irregularity development in the EEJ (Abdu 2012).
The purpose of this program was to evaluate the modulation of physiological and psychological parameters by moderate long-term training.
Moderate swimming exercise is beneficial in improving these consequences through modulation of vitamin D status.
Modulation of other JAK/STAT signaling components had mild to moderate effects on mesoderm migration.
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