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Blood tests indicated moderate liver dysfunction.
Patients with moderate liver dysfunction can take sitagliptin or exenatide [ 67, 68].
In patients with renal insufficiency, with renal clearance >10 ml/min, or in patients with mild to moderate liver dysfunction, dose adjustments of letrozole were not required (Bhatnagar et al., 1990).
The lack of accumulation of unconjugated rotigotine in patients with moderate liver dysfunction provides evidence that dose adjustment is not required for patients with mild or moderate hepatic insufficiency.
Nguyen TL et al concluded in their study on 45 patients in Vietnam, that DHF may cause mild to moderate liver dysfunction in most cases; only some patients may suffer from acute liver failure leading to encephalopathy and death [ 9].
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Nevertheless, some studies show that it is safe to use citrate in patients with mild-moderate liver dysfunction [ 14].
Statin use was associated with decreased risks of oesophageal cancer but increased risks of moderate or serious liver dysfunction, acute renal failure, moderate or serious myopathy, and cataract.
In women the NNH for an additional case of acute renal failure over five years was 434 (284 to 783), of moderate or severe myopathy was 259 (186 to 375), of moderate or severe liver dysfunction was 136 (109 to 175), and of cataract was 33 (28 to 38).
In women, the NNH for an additional case of acute renal failure over five years was 434 (284 to 783), for moderate or severe myopathy was 259 (186 to 375), for moderate or severe liver dysfunction was 136 (109 to 175), and for cataract was 33 (28 to 38).
Outcomes significantly associated with statin use were myopathy, cataract, acute renal failure, oesophageal cancer, and moderate or serious liver dysfunction (table 4).
The increased risk of moderate or serious liver dysfunction during statin use compared with the period of non-use showed a similar pattern and magnitude to the cohort analyses.
More suggestions(15)
moderate liver cirrhosis
moderate motor dysfunction
moderate liver involvement
moderate liver steatosis
moderate organ dysfunction
moderate arterial dysfunction
moderate liver lesion
moderate liver inflammation
moderate renal dysfunction
moderate biventricular dysfunction
moderate cardiac dysfunction
moderate cognitive dysfunction
moderate ventricular dysfunction
moderate liver retention
moderate diastolic dysfunction
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