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When assessing the association for wine (beer) intake, analyses were restricted to moderate lifetime drinkers of beer (wine) and spirits (below 3 g/day).
In addition, the c.1100delC mutation in CHEK2 has been identified as a susceptibility allele with incomplete penetrance and is associated with moderate lifetime risks of breast cancer.
In addition, mutations in the CHEK2, ATM and BRIP1 genes confer a moderate lifetime risk of breast cancer but are rare and account for less than 5%% of familial breast cancer cases [ 1, 2].
Both moderate lifetime severity of substance use and having any ED visits in the past 6 months significantly increased the likelihood of experiencing discrimination due to race/ethnicity/skin color in the past 12 months among non-Whites.
In addition, a number of mutant alleles have been identified in genes such as CHEK2, PALB2, ATM and BRIP1, which often display incomplete penetrance and confer moderate lifetime risks of breast cancer.
The unadjusted analysis showed that being non-White, having clinically significant mental health symptoms, moderate lifetime severity of substance use (as compared to no or low severity of substance use problems) and having any ED visits in the past 6 months significantly increased the odds of experiencing discrimination due to race/ethnicity/skin color in the past 12 months (Table 3).
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Current guidance in the UK recommends that all women aged 40 49 years with a moderate risk (lifetime risk >17%) should be offered annual mammographic surveillance (McIntosh et al, 2004).
In the UK series, all women at high or moderate risk (lifetime risk of 1 in 6 or higher [ 2, 4] based on family history were selected.
Test-retest reliability was high for prompted warning signs (r = 0.77, P <.001); prompted risk factors (r = 0.78, P <.001 b; and age invited for screening (r = 0.71, P <.001), and moderate for lifetime risk (r = 0.67, P <.001); age at risk (r = 0.60, P <.001), awareness of the CRC screening programme (r = 0.65, P <.001) and total knowledge score (r = 0.69, P <.001).
However, affective symptoms were more strongly and more diffusely associated with self-reported memory impairment, with approximately 50% raised odds of this impairment in those with moderate symptoms (lifetime and adult-onset), and nearly treble the odds in those with severe (adult-onset) symptoms in similarly controlled analyses.
Their presence in outdoor and indoor environments reflects their large emission rates coupled with moderate atmospheric lifetimes.
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