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Child characteristics (sex, race) did not moderate intervention effects.
Overall, the analysis revealed a mean effect size of d = 0.30, indicating low to moderate intervention effects.
The included trials showed inconsistent, mostly small to moderate intervention effects on targeted movement patterns.
4 Questions have also been raised about intervention reach. 2 Gender and socioeconomic status may moderate intervention effects.
Whether changes in body fat (total, abdominal) mediate or moderate intervention effects on sex hormone levels will be explored.
Van Otterloo et al. (2009) concluded that most parents in their sample were able to work with the phoneme awareness and letter knowledge programme properly, resulting in moderate intervention effects.
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In patients with low CVR, significance of a moderate intervention effect was just missed (OR = 1,90, p = 0,053; Table 3), and in patients with high CVR, there was no intervention effect (Table 2).
With a 2×3 analysis of variance design and a moderate intervention effect (Cohen's d=0.50), a total of 86 participants will be needed for a statistical power of 0.80.
Among the secondary outcomes, we did find a large and significant intervention effect on statin prescription rates in patients with manifest CVD, and a moderate intervention effect that just missed significance in patients with low CVR, but no such effect in patients with high CVR.
Ethnography's overarching goal (to understand an intervention and its impact from the participants' perspective [ 25]) dovetails with that of process evaluation within implementation science (to study what mediates or moderates intervention effects [ 26]).
Additional analyses will be conducted to confirm that treatment fidelity was equivalent across conditions and to explore dose-response relations by examining whether level of participation (e.g., attendance, number of posts, amount of help provided to others) moderates intervention effects.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com