22 The majority of adverse events were dermatologic in nature and mild to moderate in intensity (Table 3), (Galderma Ltd., study number RD.03.DEU.0485.R00, data on file, 2012).
The most consistently reported physical activity outcome across studies was the proportion of individuals achieving 90-150 minutes of activity of at least moderate intensity per week (table 3).
About 1 in 5 children had severe or very severe intensity of impacts; 18.7% had severe and 2.6% had very severe intensity of impacts.15.9% had very little, 31.1% had little and 31.7% had moderate intensity of impacts (Table 2).
It is notable that short sleepers had lower levels of physical activity of moderate-and-vigorous intensity (Table 1).
Multiple linear regression analysis showed a significant association between reduced sleep duration and increased insulin resistance (lower ISI) in the entire study sample independent of age, BMI, sex, race/ethnicity, familial diabetes risk, and daily time spent in physical activity of moderate-and-vigorous intensity (Table 2).
The primary outcome variable (ISI) and four secondary measures selected based on the outcomes of the previous regression analysis (HOMA-IR, CIR, area under the 3-h OGTT insulin curve, and fasting insulin) were compared between the two groups using ANCOVA, controlling for time spent in physical activity of moderate-and-vigorous intensity (Table 3).
The majority of AE were of mild to moderate intensity in both populations (table 2).
The ActiGraph accelerometer data revealed a significant Group × Time effect in minutes per day of moderate intensity walking activity (see Table 2), with the intervention group showing a greater increase in moderate intensity walking than the control group.
At the return visit, children in both groups achieved moderate to large changes in pain intensity (Table 2).
We do not present data on vigorous physical activity because the time spent at this intensity ranged from 0 to 2 min (see table 1, subtract moderate intensity to MVPA).
