Both groups exhibited a moderate inflammatory cell infiltration associated with discrete synovial hyperplasia (Fig. 2a,2c).
Kidneys from animals concurrently treated with VN 100 mg/kg body weight + TAA 0.03% in their drinking water showed mild to moderate inflammatory cell infiltration and tubular epithelial cell necrosis, while concurrent treatment with VN 300 mg/kg body weight provided the best morphological protection against TAA-induced renal damage.
Mild-to-moderate portal inflammatory infiltration, lower grade of endothelialitis, mild bile duct injuries, and no evident hepatocyte necrosis were detected 7 days after liver transplantation in the LV-sh4-1BB1 group.
Figure 6 shows immunolocalisation of prostaglandin proteins in membranes with a moderate inflammatory reaction, with considerable leukocytic infiltration but a relatively undiminished chorion.
Also moderate or severe inflammatory infiltrations and mild fibrosis were observed (Table 1, Figure 5).
Tumour differentiation was graded as good, moderate, poor, or mucinous (including signet-ring cell carcinomas), and inflammatory infiltration was graded as weak, moderate or strong.
The degree of lymphoplasmacytic infiltration (inflammatory infiltration) was classified as minimal (few inflammatory cells), moderate (1-2 margingin), and strong (>2 mm margin) according to the density of inflammatory cells.
The degree of inflammatory infiltration in the liver was assessed semi-quantitatively as mild, moderate or severe, based on the number of cells and cell layers in the portal areas or between hepatic cords.
At this time, only mild to moderate inflammatory changes were detected on histological examination of brain sections, with limited inflammatory cell infiltration of the meninges and the perivascular space in some vessels.
