Sentence examples for moderate immune responses from inspiring English sources

Recombinant adenovirus vectors encoding Ag85B, given via the intranasal route at six weeks of age, generated moderate immune responses and were poorly protective.

The higher sero-conversion in Group C than Group D pointed to the importance of viral replication for the immunogenicity; on the other hand, the moderate immune responses observed in Group D indicated that the HAV antigen mass included in a single dose of the vaccine were immunogenic as well.

Its low frequency of random integration into the genome and the moderate immune response make AAV an attractive platform for vector design.

The low frequency of random integration into the genome [1] and the moderate immune response make AAV an attractive basis for gene therapy vector design [2], [3].

Thus, a significant, though moderate, immune response could be detected at 7 DPI.

However, there was significant variability in antibody titers within both groups of mice, and two of the mice vaccinated with triAM1-OVA produced antibodies with titers as high as 15 000 at 56 d, suggesting that it is possible for this drug hapten scaffold to elicit a moderate immune response in a subset of the population.

A number of signal transduction pathways are involved in moderating immune responses, including the JAK/STAT (which seems to respond primarily to tissue damage), JNK (which mediates wound repair), Imd (which primarily regulates responses to Gram-negative bacteria), and Spaetzle/Toll (which generally regulates responses to Gram-positive bacteria and fungi) pathways.

In more than 250 patients with advanced cancer, moderate cellular immune responses and substantial antibody responses were noted [ 36- 39].

Intragastric feeding of SAM in rats diminished the activity of alcohol-activated innate immune pathways (Oliva et al. 2011), highlighting the potential role of SAM in moderating innate immune responses.

OVA co-delivered with biomaterial carrier vehicles supported a moderate humoral immune response that was maintained for the 18-week duration of the experiment.

He was noted to have elevated serum immmunoglobulins with a moderate polyclonal immune response (IgG 16.6 g/L, IgA 4.3 g/L, IgM 4.3 g/L).