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Conclusions This trial shows that neither moderate benefits nor moderate harmful effects of tranexamic acid in patients with traumatic brain injury can be excluded.
This is the first randomised controlled study to evaluate the effect of tranexamic acid in patients with traumatic brain injury, and we found that neither moderate benefits nor moderate harmful effects can be excluded.
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We'll try to moderate its harmful effects, but we don't dare even discuss it, much less address it as a social problem that must be addressed.
Furthermore, two of the five psychosocial resources examined (mastery and optimism) have statistically significant protective effects, and prayer moderates the harmful effects of traumatic events on self-rated health.
Population Adults and young people aged 16 or more, including subgroups of moderate, hazardous, and harmful drinkers.
Multiple studies have demonstrated that even moderate hypoglycemia is harmful and increases the mortality of critically ill patients [ 31, 32].
It considers 96 subgroups split by age, sex, mean consumption level (moderate, hazardous, and harmful), and income (low and higher income).
This includes allowing for responses to differ by population subgroups (e.g. by age, gender and drinker type, i.e. moderate, hazardous or harmful consumption and 'binge' drinker status) and different alcoholic products (e.g. beer, wine, spirits and alcopops).
The proportion of alcohol affected by a minimum unit price varied across these subgroups: for example, a 45p minimum unit price would affect 12.5%, 19.5%, and 30.5% of units sold to moderate, hazardous, and harmful drinkers, respectively.
10 The model estimated changes in consumption and the levels of harms over a 10 year period after the introduction of the policy, examining 54 subgroups of the population based on age, sex, and three levels of consumption (moderate, hazardous, and harmful).
Craigslist's defense was straightforward and logical – they complied with the law and they went beyond the law in moderating and tracking harmful listings.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com