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It is unknown to what extent bolus infusion of hydrocortisone increases glycemic variability and adjustments in insulin infusion rates in patients under moderate glycemic control.
The results of this retrospective analysis of blood glucose levels and insulin infusion rates in ICU patients under moderate glycemic control show that bolus infusion of hydrocortisone is associated with higher glycemic variability and insulin rate variability, more frequent BG measurements and a greater need for insulin boluses.
These patients were mostly experienced insulin pump users and had moderate glycemic control at baseline (7.8 ± 1.0% HbA1c).
Moderate glycemic control (6.1 8.0 mmol/L) after cardiac surgery was found to reduce the duration of ventilation [ 29].
Injectable GLP-1RAs provide substantial glycemic control and weight reduction; while oral DPP-4 inhibitors provide moderate glycemic control and weight neutrality.
Health systems may consider prioritizing care to include smoking cessation, increasing physical activity, and moderate glycemic control among patients with diabetes.
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102 Thus, trials investigating the use of new technology to moderate behavior, glycemic control, and well-being have produced some positive data.
Indeed, avoidance of hypoglycemia is of major importance in brain-lesioned patients, which explains our moderate regimen for glycemic control (target range 80 140 mg/dl) [ 1].
The results from these 6 trials in humans show moderate improvements in glycemic control and in metabolic markers using RR-bromocriptine to treat patients with T2DM.
In addition, a prospective randomized study found no differences in the rates of POAF events and wound infection between aggressive (5.0 6.6 mmol/L) and moderate (6.6 10.0 mmol/L) glycemic control [ 34].
In a recent study, the use of premixed lispro with neutral protamine lispro in a 50 50 ratio for the evening meal and regular human insulin with NPH in a 30:70 ratio at the early morning meal during Ramadan compared with regular human insulin at 30:70 twice daily was associated with moderate improvement in glycemic control and hypoglycemia (40).
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