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More recently, pirfenidone and nintedanib, two compounds with pleiotropic mechanisms of action, have proven effective in slowing functional decline and disease progression in IPF patients with mild to moderate functional impairment, highlighting the importance of timely diagnosis and administration of treatment in early stages of disease.
First, resident physicians assessed the value of living with mild to moderate functional impairment from CHF to be relatively high.
Participants had a mild to moderate functional impairment as measured by ADL and IADL scales (M = 6.53, s.d. 3.8).
Forty percent of stroke patients exhibit moderate functional impairment, and 15%to30%0% exhibit severe disabilities [ 1].
Patients in Class 2 (24%) showed moderate functional impairment on the QLS and SOFI, and moderate severity in psychopathology on the PANSS.
Baseline disease characteristics of mean C-reactive protein level (2.0 mg/dL) and Health Assessment Questionnaire-Disability Index score (1.4) confirm that the overall pooled safety population entered the trials with inflammation and moderate functional impairment (table 3).
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The Measuring Eating, Activity, and Strength: Understanding the Response — Using Protein (MEASUR-UP) trial is a randomized controlled pilot study of obese women and men aged ≥ 60 years with mild to moderate functional impairments.
Mean scores on the three AUSCAN subindices and global rating of disease also reflected moderate pain, functional impairment, and impact of disease on patients' sense of well-being.
This physical impairment was confirmed by the FIRS scores, indicating moderate function impairment.
Emboldened words: the difference from original HFS-30 ICC: intraclass correlation coefficient The severity of HFS was scored based on the five point scale (0: normal, 1: slight disability, 2: moderate disability, without functional impairment, 3: moderate disability, with functional impairment, and 4: severely incapacitated).
To evaluate the efficacy and safety of botulinum toxin type A (BoNT-A) injected intra-articularly in 60 subjects with moderate pain and functional impairment secondary to knee osteoarthritis.
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moderate functional recovery
moderate visual impairment
moderate functional difficulty
moderate functional alteration
moderate functional improvement
moderate functional limitation
moderate functional gain
moderate functional disability
moderate functional capacity
moderate functional status
moderate functional antagonist
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