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At the time of study entry, our patients showed moderately to severely active disease (mean DAS28 (± SD) 5.2 ± 1.2) and moderate functional disability (mean HAQ (± SD) 1.26 ± 0.8).
According to the HAQ-DI score, at least moderate functional disability was observed in 94 out of 444 (21.1%) patients, of whom 72 (16.22%) showed moderate disability and 22 (4.95%) showed severe disability.
Disease activity in the RA group was characterized by high median tender (31) and swollen (28) joint counts, prolonged morning stiffness (median duration 60 minutes), a median erythrocyte sedimentation rate of 26 mm/hour, a median CRP of 13 mg/l, and moderate functional disability (median mHAQ score 1.62).
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Forty percent of stroke patients exhibit moderate functional impairment, and 15%to30%0% exhibit severe disabilities [ 1].
With the migraine diary one can rate headache severity (none, mild, moderate, severe) functional disability (none, mild, severe, bed rest) and associated symptoms (nausea, vomiting, photo/phonophobia).
Persons with moderate to severe functional disability were functionally disabled in either two (2%), three (14%), four (46%) or five (38%) SMAF domains.The prevalence of moderate to severe multidimensional functional disability (32%), varied according to the different SMAF dimensions/domains: it ranges from 7% (ADL) to 86% (IADL), as illustrated in Figure 1.
185 patients (49.3%) had more than two comorbidities (multipathological) and 183 (48.9%) moderate to severe functional disability.
In total, 53.9% had more than two comorbidities (pluripathological) and 31.5% moderate to severe functional disability.
All older people with a moderate to severe functional disability (32%) have a disability in at least two SMAF domains.
In the 18 alive patients, 67% presented a rheumatic flare (10 of 15 available data) and 7 moderate to severe functional disability of the infected joint (39%).
In each domain, the prevalence of moderate to severe functional disability, and thus the need for supervision or assistance, varies across activities/items within a specific domain, as illustrated by Table 1.
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