Sentence examples for moderate functional antagonist from inspiring English sources

These compounds displayed subnanomolar hNK1 affinity along with good efficacy in a gerbil foot-tapping (GFT) model, but unfortunately they had low to moderate functional antagonist (IP-1) activity.

Conclusion: Prevention of functional decline should target chronic conditions and moderate functional limitation in older adults.

Aripiprazole acts as a functional antagonist in a hyperdopaminergic environment and a functional agonist in a hypodopaminergic environment (Keck and McElroy 2003).

Prior moderate functional limitation, CVD, and vision impairment predicted onset of severe functional limitation after controlling for demographics.

Results: Gender and race predicted moderate functional limitation onset, after controlling for age and education.

In functional antagonist assays, a dose-response curve measures the effect of the ability of a range of concentrations of antagonists to reverse the activity of an agonist.

Moderate functional gain with increasing nβ, primarily in terms of improved fb and λ, is observed.

Only one patient (5.9%) had moderate functional limitation post-operatively.

Attempts to block RAGE, the most studied receptor for HMGB1, using a receptor antagonist failed as we could not define a functional antagonist.

We next addressed whether FAIM-L serves as a functional antagonist of A β-induced neuronal death.

Thus, A-792611 was reported to be a functional antagonist of PXR in human but not rat hepatocytes [ 74].