Cross-validation based determination of confidence levels of the included model reactions (Additional file 1: Table S7) show high or moderate confidence for approx. 80%% of the reactions, indicating that only approx. 20 % of the reactions did not have expression based support, i.e. were added by FASTCORMICS to generate a consistent network model.
PFO closure may be associated with six fewer TIAs over a period of 5 years (CI 15 fewer to 9 more, moderate confidence because of risk of bias (figure 3, table 3).
PFO closure may have no effect on major bleeding over a period of 5 years (CI 10 fewer to 20 more, moderate confidence because of risk of bias, table 3).
All diagnoses were given a confidence rating using a 5-point scale: 1-highest confidence of fvCBS, 2-moderate confidence of fvCBS, 3-equivocal rating, 4-moderate confidence tpvCBS, 5-highest confidence of tpvCBS.
This means we can have only moderate confidence in the magnitude of these effects.
For example, prospective cohort studies usually have all three remaining features and receive an initial rating of "moderate confidence," whereas a case report may have only one key feature and receive an initial rating of "very low confidence" (see Supplemental Material, Table S2, for key features for standard study designs and discussion, pp. 9 11).
The disclosure on Thursday that the Defense Intelligence Agency had determined with "moderate confidence" that North Korea was capable of making a nuclear weapon small enough to be delivered by a ballistic missile was the subject of much attention here.
The Defense Intelligence Agency rang alarms bells on Thursday with a report that it had concluded with "moderate confidence" that the North was capable of launching a missile with a nuclear warhead.
Fifty-four percent of students reported a moderate confidence in their knowledge about radiation and risks.
The Defence Intelligence Agency DIAA) report said it concluded "with moderate confidence that the North currently has nuclear weapons capable of delivery by ballistic missiles".
"We assess with moderate confidence that Tehran had not restarted its nuclear program as of mid-2007," the N.I.E.
