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Only about a quarter of patients in the mindfulness group reported a decrease in pain substantial enough to be considered of even moderate clinical importance.
Findings of moderate clinical importance did not require immediate further diagnostic workup or therapy, but would likely to be verified later on either by chart review or by further clinical or radiologic follow up.
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Most alerts were of serious (52%) or moderate (45.1%) clinical importance.
Nephrologists as subject matter experts verified moderate to significant clinical importance for the individual adverse effects to be used in the scoring system and substantiated content validity [ 18].
The nephrologists' survey confirmed that the adverse effects scoring system provided moderate-to-significant clinical importance (3.1 ± 0.75 with maximum score of 4.0) for the assessment of the 18 adverse effects in renal transplant recipients.
The potential for AEs related to n-3 supplementation in older adults appear mild-moderate at worst, and not of clinical importance.
The underlying assumption is that the changes from negligible to mild, from mild to moderate, and from moderate to severe are roughly equal in terms of clinical importance.
Because of the clinical importance of high-grade (moderate or severe) ESD (Wang et al, 2005; Taylor et al, 2013), these statistics were also calculated for identification of patients with a histologic diagnosis of high-grade ESD.
There are important issues of clinical importance.
However, the fair to moderate agreement observed for assessment category 3 is of clinical importance.
Whereas the majority of the findings were of low clinical importance, 35.2% were considered of high and moderate clinical significance.
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