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In all these apoptotic parameters, moderate changes caused by individual agents in CML-T1 or no apoptotic effect of SAHA on HL-60 cells in contrast to large apoptotic effect after 48 h of concurrent drugs action have been detected in both cell lines.
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Because of the moderate and stable diabetic state, this rat model is useful for investigating the retinal microcirculatory changes caused by type 2 diabetes over an extended period of time (Miyamoto et al., 1996).
He said the recommended changes were not needed anyway, because the Australian Prudential Regulation Authority introduced regulatory changes last year to the way banks can lend to investors, with those changes causing Sydney's and Melbourne's property markets to "moderate" over the last six months, which was a good thing.
These changes cause downregulation of Erk pathways.
A spatial variation in stressing rate of the upper crust beneath the NKTZ is estimated using a response of the normalized time delay to a step-wise stress change caused by a moderate-sized earthquake.
We estimate a spatial variation in stressing rate of the upper crust beneath the high strain rate zone based on a response of the normalized time delay to a step-wise stress change caused by a moderate-sized earthquake.
From this result, together with a temporal change in time delay due to a step-wise stress change caused by a moderate-sized earthquake (Hiramatsu et al., 2005), we estimate a spatial variation in stressing rate of the upper crust beneath the NKTZ and conclude that the high strain rate in the NKTZ is attributed to the high deformation rate below the brittle-ductile transition zone in the crust.
BA also caused moderate changes in the expression of cyclin E protein at 30 μM concentration.
While conventional management strategies with a short logging cycle (here 20 years) produce low yields and cause severe changes in tree species composition, a reduced impact logging strategy with a longer cycle (here 60 years) leads to relatively high yields and causes moderate changes in species composition.
The change caused alarm and misunderstanding.
As demonstrated by data obtained from ARE-dependent luciferase reporter gene assay and qRT-PCR analysis, a loss of Nrf2 phosphorylation caused only moderate changes in the transcriptional activity of Nrf2 (Figure 2 and 3).
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