Sentence examples for moderate agonist effect from inspiring English sources

It displayed a moderate agonist effect and selectivity for the CB1 cannabinoid receptor [11].

As a partial opiate agonist, buprenorphine is likely to have more moderate opiate agonist effects than full agonists such as physeptone.

Its pharmacological mechanism is due to an agonist effect on gamma-aminobutyric acid (GABA) receptors [2].

Its pharmacologic mechanism is related to the agonist effect on gamma-aminobutyric acid (GABA) receptors [2].

Norepinephrine is a potent α1-adrenergic agonist with a weaker but still significant β-adrenergic agonist effect.

Drawbacks include hot flashes, lack of bone agonist effects and unknown efficacy under conditions of moderate to high circulating endogenous or exogenous estrogen levels (premenopausal women or postmenopausal women receiving HRT).

Another anti-oestrogen agent, fulvestrant, is an ER antagonist, and unlike tamoxifen, has no agonist effects.

These agonist effects may, however, limit efficacy.

The signaling pathways of such agonist effects are poorly understood.

Less than additive, weak agonist interactions are observed with mixtures in in vitro AHR assays, where the concentration of potent agonists is significantly lower than those of more moderate agonists (Safe 1997 1998).

It has been reported earlier that lack of enough number of TR/pMHC structures makes differentiation of weak- and moderate-agonists from strong-agonists or true-agonists from antagonists, almost impossible without immunological assays [15].