Sentence examples for moderate affinity of from inspiring English sources

Binding parameters calculated by Stern-Volmer method showed that ferulic acid binds to α2M with moderate affinity of the order of ∼104 M−1.

These molecules contain two binding moieties, each of which in isolation has only a moderate affinity of binding, which are linked together by a flexible peptide bridge.

Our kinetics studies demonstrated that the nature product chrysin exhibited a high inhibitory affinity of 54 nM towards human cytochrome P450 1andand was comparable to α-naphthoflavone (49 nM), whereas it represented a moderate affinity of 5225 nM against human cytochrome P450 2C9.

However, the values of Δπmax were of low magnitude (Table 2), which indicated a moderate affinity of the peptide for these gangliosides compared with GalCer-HFA.

The moderate affinity of Hox3 for Xlox in our analyses may be due to convergence or it may represent a bilaterian-specific duplication.

The best improvements in reactivity for the same catalytic domain (~4×) were correlated with broad specificity and moderate affinity of CBM binding.

Faster nucleation and growth of gold nanoparticles is therefore likely observed in cases of polymers that have moderate affinities of interaction with gold or those with an increased number of tertiary amines.

Their initial evaluation has shown a moderate affinity for MDM2 and induction of the p53 pathway in tumour cell lines (Zhao et al, 2002).

36 Because of its moderate affinity for the α2 adrenergic receptor, aripiprazole may produce comparatively less orthostasis, leading to greater tolerability.

Importantly, molecular strategies for the in vivo imaging of the TSPO require moderate affinity for the target as high-affinity ligands tend to accumulate on to the vascular-binding sites masking the TSPO in tissue.

Several studies have shown that omeprazole carries a considerable potential for drug interactions because of its high affinity for CYP2C19 and moderate affinity for CYP3A4.