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Nonlinear stochastic differential equation models with unobservable state variables are now widely used in analysis of PK/PD data.
The usual mixed model methodology cannot accommodate models with unobservable incidence matrices.
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The reason is that economists became convinced that the phenomena that couldn't be explained by the approximation that individuals maximize expected value were of central importance, and justified a model with unobservable personal parameters of risk aversion.
Map adaptation, by construction, gives marginally stable models with locally unobservable modes, that are handled.
We use the British Household Panel Survey to test and confirm the model predictions, and deal with unobservable heterogeneity employing three research designs individual fixed effects, housing-spell fixed effects, and instrumental variables.
Additionally, we estimated linear regression models with physician fixed effects to eliminate unobservable, time invariant differences in physicians associated with both higher average intensity of care and malpractice risk of physicians.
Not unnaturally, the suggestion that space was filled to infinite density with unobservable particles was not easily accepted in spite of the obvious successes of the theory.
This holds only, however, if the treatment effect does not vary with unobservable characteristics.
As a whole, 103 assigned residues are used except 5 residues with unobservable resonance signals.
Note also that the iBay software models the unobservable scale of this threshold trait such that the residual variance is fixed at 1.0 (i.e., σe2 = 1).
A model, ("underlying model" of an unobservable underlying variable responsible for ranks) exists.
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