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To achieve this goal, a generation of genetic models with selective NK cell deficiency, and development of reagents (antibodies) for visualizing subsets of NK cells in situ will be necessary.
And how fast does it turn over compared to full-length TTN? Models with selective disruption and tagging of this isoform should begin to answer these questions.
The recent development of specific knock out mouse models with selective reduction in individual intestinal cDC populations has also allowed researchers to start addressing the functions of individual intestinal cDC subsets in the regulation of adaptive immune responses in vivo.
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On the other hand, a competitive insurance model with selective contracting of health care providers by health insurers and flexible pricing of health services is offered too.
All numerical results are calculated by a finite element model with selective reduced numerical integration based on the first-order shear deformation theory.
All these results correlate well with our intuitive ideas about an evolutionary model with selective pressure.
Propagator ratios, in particular, are more sensitive to the mode of evolution than the qualitative shape of strain trees, which is reproduced by any model with selective sweeps.
Using both intact mice with targeted knockout of PPARγ in prostate epithelium and a tissue recombination model with selective gene modulation in the epithelial compartment reduced PPARγ function was associated with increased activation of oxidative stress, autophagic activity, and activation of pro-inflammatory signaling pathways.
By using a mouse model with selective deletion of BK channels in hair cells (HC-BK−/−), leaving their expression in other peripheral and central parts of the body intact, we examined the importance of hair cell BK channels for central auditory processing.
In this article we describe a framework for data-driven evolution of static mechanistic models with a selective inclusion of simple empirical terms.
An important thing is that the codon models with the selective constraints estimated from nuclear DNA or by the physico-chemical method yield a much smaller value of AIC than the mtREV-1-F.
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