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Using organotypic skin models with primary keratinocytes from atopic dermatitis patients and controls, van den Bogaard et al. [ 86] demonstrated that coal tar activates AhR, resulting in the induction of epidermal differentiation (i.e., upregulation of filaggrin, loricrin, and hornerin expression), and thickens the cornified layer.
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Two degrees-of-freedom car model with primary and secondary suspension system have been adopted by Cai et al. [10] and Cai and Chen [11] to study only vertical motion of the vehicle.
It was shown that a syngeneic tri-culture model with primary rat brain capillary endothelial cells, astrocytes, and pericytes yielded highest transendothelial electrical resistance (TEER) values [ 15].
For the first time we used this approach on a cell culture model with primary HNSCC cells mimicking a common therapy regime for HNSCC [ 4].
Because the pladienolide B derivative showed in vitro antitumor activity against primary cultured gastric cancer cells, we investigated its effect in vivo using a xenograft model with primary cultured cells.
A monthly income > 3000 Euro was associated with less satisfaction with nurses' or radiation therapists' information provision, but this was only significant in the model with primary cancer (Tables 4 and 5).
The likelihood-ratio test of the null model with primary care centre as a random factor versus usual linear regression was significant (χ2 = 24.19, P < 0.0001) and its variability was considerably higher than when using the psychiatrist as random factor (χ2 = 13.79, P < 0.0001).
> -wrap-foot> Model 1: unadjusted hazard ratio; model 2: Model 1 with additional adjustments for hemoglobin, serum albumin, total cholesterol, and C-reactive protein levels; Model 3: model 3 with primary diagnosis, emergent surgical procedure and age-adjusted Charlson comorbidity index.
The army of the Commonwealth was organized along several different models, with the primary division being that into two 'contingents' or 'enlistments' (or in Polish: autorament): national and foreign.
In animal models with resected primary tumors, SPM demonstrated greater inhibition of 4T1luc cell dissemination and fewer signs of toxicity compared with Duopafei.
In animal models with unresected primary tumors resected, SPM at a safe dosage (10 mg DTX/kg body weight) remarkably inhibited BC metastasis to distant major organs such as the lungs and liver compared with Duopafei.
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