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Some works have explored the scaling of optimization algorithms to build large-scale models with numerous parameters through distributed computing and parallelization [9, 18, 20, 21].

In the context of systems biology, computer controlled experimenting as we implemented provides an extremely effective way of generating the large amounts of quantitative data needed for parameterizing and validating complicated models with numerous parameters.

(2248) Neural network models with numerous descriptors were used to predict oral bioavailability.

Third, the low number of patients in group 4 might introduce significant interference in the use of statistical models with numerous covariates.

Two models with numerous equations, for example, can integrate easily if they are in the same programming language, have similar time scales, belong to the same knowledge domain and were developed on the same hardware and operating systems.

Other studies using CX3CR1-deficient mice showed exacerbated levels of phospho-Tau and elevated Tau pathology in Tau transgenic mice [ 9, 22], while CX3CR1 deficiency reduced amyloid load in AD mouse models with numerous Aβ deposits [ 71, 74].

Similar(54)

Therefore, when the law takes effect after the governor signs it, it will initially closely follow the Oregon model, with numerous statutory procedures and safeguards meant to protect patients against coercion or changes of heart.

Straightforward Markov Method applied to solve this problem requires building a model with numerous numbers of states and solving a corresponding system of differential equations.

It is based on a physically motivated dislocation density evolution equation originally intended for use in a detailed FEM analysis, where individual grains are modeled with numerous finite elements.

For example, the mutual information measure of conditional dependency between two variables is an elegant way of identifying and quantifying dependencies between elements in a system that may not be immediately obvious, especially in a complex situation involving a model with numerous inputs, nodes, and interactions.

Although model predictions are presently limited by the few clear examples of ring species, the discovery of new ring taxa will allow iterations of this same model with numerous and biologically diverse taxa.

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