We have created a comprehensive FH stem cell model with differentiated hepatocytes (iHeps) from human induced pluripotent stem cells (iPSCs), including genetically engineered iPSCs, for testing therapies for FH.
Thus, the design of a co-culture system based on 1 20 (w/w) collagen:PCL biocomposite membranes for preparation of a bi-layered skin model with differentiated epidermal sheet was proven in principle.
Moreover, many studies have used osteoblast and bone marrow-derived mesenchymal stem cell models with more differentiated osteogenic phenotypes than PDLSCs, indicating the cell-type specificity of responses on Ti substrates.
HTC's CFO confirmed that "a classic version" of the company's flagship One M9 that's more "trendy" is in the pipeline, alongside another model(s) with differentiated features.
Stem cell-derived models offer promise, with differentiated hepatocyte-like cells currently considered to be "fetal-like" in their maturity.
Using a novel approach to the evaluation of new network technologies that combines an engineering cost model with a differentiated multi-player oligopoly model with wholesale access regulation this article evaluates the choice among different Fibre-to-the-Home (FTTH) architectures.
It introduces search costs and switching costs into a version of Perloff and Salop's (1985) model of oligopoly with differentiated products.
We address this important preoccupation within the Adaptive Semantic Web framework by pretesting MOOC learners on their actual competencies within a shared competency model to form sub-groups with differentiated learning scenarios.
Separate models were fitted for each of the three intermediate endpoint datasets, with additional models that differentiated between costs incurred in the first year post-event and in subsequent years for the non-fatal stroke and non-fatal cardiac event endpoints [ 11].
But the Dixit-Stiglitz model, with its subtly differentiated firms competing for variety-loving consumers, lent itself to explaining why Germans might import Renaults, even as the French imported Volkswagens.Mr Krugman's model showed that when trade barriers fall, firms gain access to bigger markets, allowing them to expand production and reap economies of scale.
