Sentence examples for models which develop from inspiring English sources

For in vivo MRI studies, the engineered nanocages were evaluated using the KrasG12D; Trp53R172H; Pdx-1Cre (KPC) transgenic mouse models, which develop clinically relevant pancreatic tumor under normal processes of angiogenesis, immune function and inflammation.

This has been partly circumvented through the use of non-human primate models, which develop a form of TB that exhibits many of the hallmarks of the human infection [12].

Xenograft models provide a complement to genetically engineered mouse models which develop over a longer time and reside in an immunocompetent host but do not always capture all aspects of human cancer.

The classes of genes discovered as dysregulated are particularly interesting because they are similar to classes of genes found dysregulated in two mouse models which develop PAH, including mice expressing a BMPR2 mutation and mice with a vasoactive intestinal peptide (VIP) knockout.

We used an adeno-associated virus (AAV) delivery approach to assess the potential effect of TFEB in 5xFAD (Oakley et al, 2006) and rTg4510 (Ramsden et al, 2005; Santacruz et al, 2005) transgenic mouse models, which develop progressive Aβ and NFT neuropathologies, respectively, starting at approximately 2 months of age.

The process resembles the development of cancer in humans to a larger extent than several transgenic mouse cancer models, which develops cancer considerably shorter period of time.

A geometric model, which develops the basis of a ray-tracing technique for performing the optical analysis, is also described.

In the traditional management theory the so-called agency model, which developed to support industrial work the relationship between the employee ("agent") and the employer ("principal") is oppositional, and workers' motivations are external.

In its final years the company also designed and produced the unusual three-cylinder 58JS3C model, which developed 4050 kW at 220 rev/min and was specified to power several small container ships.

We have recently characterized a rat ciliopathy model which develops primary photoreceptor degeneration and secondary vasoregression.

Indeed, in earlier studies, using a MPTP-treated mouse model which develops tauopathy, we have shown that activated p-GSK-3β co-immunoprecipitates with α-Syn and with pSer396/404 Tau [24].