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In other words, the PIP is the sum of PMPs for all models wherein a covariate was included.
One limitation of this gradient-generating model is that it does not consider the source of the axonal tip signal; therefore, we examined a second family of models wherein a cell body signal is anterogradely transported by kinesin motors to the neurite end, where it activates dynein-mediated retrograde transport of another cargo (or a modified version of itself) to the cell center.
MRL models belong to the class of non-convex nonlinear models wherein a number of difficulties may arise when estimating parameters of a realistic dynamical system, like e.g. convergence to local solutions, flat objective function in the neighbourhood of the solution and unreasonable computational effort for a problem with a large number of parameters.
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Sadasivuni et al. (2013) developed such a model, wherein a gravity model was used to measure the interaction among cities.
For example, the cross-sectional area of the blood flow was shown to reduce by 50%% in a model wherein a 12-Fr sheath (diameter 4 mm) is inserted in an artery with 5.6-mm diameter (the size of the femoral artery in our case) (Fig. 2).
It was found that the classical raft model, wherein a fixed number of lipid rafts accommodate a fixed fraction of raft-inserted proteins, is incompatible with the observed gold point patterns [11].
We proceed by formulating a collective network inference model, wherein a network is jointly estimated from multiple nonidentical data distributions.
We present evidence in support of the 'sliding model' wherein a RecA filament diffuses along a dsDNA track.
An alternative is to fit a stratified model, wherein a covariate that displays nonproportionality is modelled without the constraint of proportionality.
If IBS-C is similar to the CDI model wherein a pathogen produces toxins that inhibit intestinal motility, use of FMT could be a viable treatment option.
A working model, wherein a cycle of H2B ubiquitination/deubiquitination specifies Ser2P to regulate elongation and 3'-end processing of JAK-STAT inducible mRNAs is proposed.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com