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Decisions between various models were informed by statistical considerations but also by a consideration of what is generally regarded as HRQoL.

The models were informed with assumptions about treatment patterns from the pediatric authors, who are based at one of seven centers.

These models were informed by our field data and by previous reports of the genetics of Bt resistance in S. frugiperda[ 11, 21].

The variants chosen for inclusion in risk prediction models were informed by an extensive literature review of genetic risk factors for CRC completed by the authors (Campbell et al. 2009).

Similar to the CODEm models, the modeling procedure for LRI and diarrhea etiology models used hierarchal spatial effects by which country models were informed by data from the country, region, and super-region only.

Similar(55)

The selection of covariates included in multivariable models was informed by the literature.

Participants proposed that the dichotomy be set aside and concluded that selection of low-dose extrapolation models be informed by categorization of mechanisms of toxicity, such as genotoxic, epigenetic, or cytotoxic processes, and by population-level factors (e.g., susceptibility).

Selection of predictors, both fixed and random effects, for inclusion in the models was informed using backward stepwise selection methods where covariates below the specified significance level (p < 0.05/t < 2) were identified and removed.

The selection of independent variables included in our regression models was informed by previous studies examining the effects of insurance enrolment in developing countries (Schneider and Diop 2001; Jowett 2003; Jütting 2004).

We outline the key insights which models have given on the dynamics of Ascaris transmission, describe the model structures and discuss how current and future models are informing the design of control programs in the era of both increased access to donate drugs and new statistical techniques to validate these models against reinfection data.

The model is informed by published information on tephra clean-up operations from volcanic eruptions and urban areas around the world.

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