Being designed as generic theoretical frameworks SDH models are bound to a certain level of abstractness and detachment.
In the absence of a structured effort to represent available knowledge in a mechanistic way, such models are bound to yield predictions of questionable reliability.
Bad models are bound to lead to bad decisions, so the better models we have, the more likely we are to discover and cost-effectively develop drugs that work well to help patients.
"Animal models of diseases are absolutely critical in the drug development process... Bad models are bound to lead to bad decisions, so the better models we have, the more likely we are to discover and cost-effectively develop drugs that work well to help patients" What do you feel is the main benefit of the journal in this field of science and how would you like to contribute in your new role?
Given the competition among record companies, the subscription model is bound to be tricky to organize and implement.
Given recent stockmarket turbulence, the KMV model is bound to show some increase in risk.
It also hopes that tighter budgets may prompt governments to continue to flog assets.Long-term concerns over Macquarie's model are bound to persist for as long as the world is worried about financing, accounting, disclosure and complex financial structures.
Blockchain technology will change, not only our Network but the employee benefits industry as we know it". A move away from batch executions: At present, the business model is bound to fixed deadlines as everything is done quarterly with a number of delays after the closing of the quarter.
Accurate phylogenetic reconstruction is probably one of the most pressing issues, since such modeling is bound to play an increasing role in our data analysis routines.
A molecular regulatory network model is bound to have several parameters, for most of which very little empirical data is available.
And that built-in itch to turn the page appears impossible for the industry to shake — unsurprisingly so, given business models were bound so tightly to upgrade cycles for so many years.
