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Conversely, using a panel of cell line-derived three-dimensional models, we showed that ERK5 inhibition markedly suppresses the molecular and functional features of colon cancer stem-like cells.
Despite the discussed restrictions in our models, we showed, to our best knowledge for the first time, the benefits of using LSP metrics with a 30 m × 30 m spatial resolution for carbon modelling, contributing to the body of research that employ LSP metrics for carbon estimations (e.g. [66 68]).
Finally, using mouse PDA models, we showed that shRNA knock-down of ANXA2, a mutation at tyrosine 23, or anti-ANXA2 antibodies, inhibit PDA metastases and prolong mouse survival.
Using culture models, we showed that H2O2 enhances the generation of β-cells in the rat embryonic pancreas.
By testing alternative mediate models, we showed that the one we described is the best fitted to account for the relationship between these three variables.
In addition, using cell line models, we showed that unlike protein marker-based detection methods, CTCscope only detected viable CTCs with intact RNA, excluding dead cells from enumeration.
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Using conditional probability-based models, we show that splicing events are coordinated across these sites.
Using cell and mouse models, we show that the S100P decoy function of NORAD suppresses lung and breast cancer migration, invasion, and metastasis.
Based on projections from our growth models, we show the substantial potential scope for state economic development through improving the quality of schools.
Here, by extensively analyzing PD patient brains and neurons, and fly models, we show that alpha-synuclein accumulation results in upregulation of Miro protein levels.
Using a combination of mechanistic and statistical models, we show that much of this increase can be attributed to climatic trends in Northwest states, in particular cooling of growing season nighttime temperatures.
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CEO of Professional Science Editing for Scientists @ prosciediting.com