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Sukhai's doctoral research involves using transgenic mouse models to study the pathogenesis of acute promyelocytic leukemia.
Further development of skin tissues constructed with iPSC-derived cells will generate versatile models to study the pathogenesis of skin disease processes and to test the safety and efficacy of new products and drugs designed to treat these diseases.
Researchers have had few suitable animal models to study the pathogenesis of CHM.
Mice deficient in the telomerase gene products are well established and potentially very good models to study the pathogenesis of telomerase-related bone marrow failure, as already reported [50].
Researchers use different routes of delivery of B. pseudomallei in experimental models to study the pathogenesis of the disease and the induction of host protection.
Also included are presentations on persistent infection and suppression of host response by alphaviruses, subversive neuroinvasive strategy of rabies virus, neurovirulence and host factors in flavivirus encephalitis, regulation of apoptosis by viruses infecting insects, and Semliki Forest virus infection of laboratory mice as models to study the pathogenesis of viral encephalitis.
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Recently, we created a Drosophila model to study the pathogenesis of optic atrophy.
These results emphasized the importance of using a physiologically relevant respiratory epithelium model to study the pathogenesis of influenza virus.
In conclusion, we have established a reproducible model to study the pathogenesis of TBM in the zebrafish.
An interesting alternative animal model to study the pathogenesis and therapy of infections is the use of invertebrate hosts [ 35].
G. mellonella, is a reliable model host to study the pathogenesis of numerous human pathogens [ 62].
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