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We will develop models to stratify patients according to their risk of adverse outcomes.
The predicted 10-year CVD risks are calculated using risk score models to stratify individuals against the treatment thresholds for various risk score models.
Further investigation of predictive models to stratify risk of non-sentinel lymph node metastasis will better define their role in guiding clinical decision-making, while we await the results of larger randomized trials.
Further, the 10-year CVD risks are calculated using risk score models to stratify individuals against the treatment thresholds of the various models, and are not prospective CVD events.
49 There are currently no accurate prognostic models to stratify patients with SCC and to help guide clinical decisions, leading to a lack of uniformity in the management of the tumour.
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To confirm the ability of this model to stratify drugs based on mechanistic of action, future studies should be undertaken with drugs from additional mechanistic classes.
In preparing to proceed to Phase 4 validation, we developed a prediction model to stratify BE patients, validated our model, and estimated its potential clinical impact (endoscopy savings) by applying a simulation.
Retrospective six-monthly CD4 T-cell counts were utilised in a multilevel regression model to stratify the cohort into HIV disease progression groups based on individual participant CD4 slopes.
We have derived and successfully tested a biomarker-based risk model to stratify pediatric septic shock outcome.
With an abundance of available drugs and targeted therapies today, the number of available treatment options for each patient is increasing, and there is a necessity for a preclinical model to stratify each patient to the optimal treatment option [ 52].
6 For these analyses, which were prespecified in the planned statistical analysis, we used the prognostic model to stratify patients in the CRASH-2 trial whose treatment was initiated within three hours after injury into four strata of risk of mortality (<6%, 6-20%, 21-50%, >50%).
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