Sentence examples for models these compounds from inspiring English sources
In some of the models these compounds showed anxiolytic properties, while in others they were ineffective or even anxiogenic.
In animal models, these compounds seem to affect glucose homeostatic pathways, which eventually lead to hyperglycemia (2).
The best equilibrium isotherm models of these compounds were used to calculate the high-concentration band profiles of different substrates on the MIP and the NIP with the POR model.
The results from the RIOPA study can potentially provide information on the influence of ambient sources on indoor air concentrations and exposure for many air toxics and will furnish an opportunity to evaluate exposure models for these compounds.
Given a test compound, LLL method firstly find its k nearest neighbors in the training set by using a predefined property set (molecular fingerprints or descriptors), and then build local models using these compounds to predict the value of the test compound.
The lack of human efficacy of TZDs towards cardiovascular disease in initial trials [ 29] is surprising in view of the overwhelmingly positive occurrence of beneficial actions in cell and animal models for these compounds [ 30- 33].
Kinetic analysis suggests competitive inhibition and the binding model of these compounds can be rationalized using molecular modelling studies.
Our calculations provide a complete and atomic-level-based model for these compounds' free energy and shed some light on the ongoing search for the precise structure of dynamically stabilized high temperature phases in SMAs.
The order of interaction energies predicted by molecular modeling of these compounds is associated with their experimental IC50 values with GIIAPLA2 used as a target.
It is not clear the degree to which the in vitro assay of potency actually reflects the in vivo activity, and the efficacy and low toxicity shown in the orthotopic model suggests these compounds could prove useful clinically.
This finding could have not been predicted on basis of the effects of DL-sulforaphane and allyl sulfide in this model because these compounds are thought to activate Nrf2 signaling by disrupting the Nrf2-Keap1 interaCuadradouadrado et al., 2009).
