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In both the Emx1-Cre and Dlx5/6-Cre conditional mouse models the latency to scPTZ-induced seizures was significantly shorter than for their wild-type littermates.
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The effect of using time delay to model the latency period of Chlamydia trachomatis infection is explored, by designing a deterministic two-sex model for Chlamydia transmission dynamics in a population.
Furthermore, this study shows that adding a time delay (to model the latency period) does not alter the main equilibrium dynamics (with respect to the effective control or persistence of the disease in the community) of the corresponding non-delayed Chlamydia transmission model considered in our earlier study Sharomi and Gumel (2009) [7].
In our experimental model the latency of the disease was much longer (median survival 611 days in control animals) compared to the other routes of administration.
However, we did incorporate time dependent functions to model the latency between change in exposure and changes in lung cancer mortality.
We need to explicitly model the latency period to take into account not only exposures of direct interest (arsenic in our example) but also additional risk factors (such as smoking) that might decrease the latency period and accelerate disease onset.
According to the literature, food insufficiency may contribute to dementia through two potential models, namely the latency and pathway models.
These observations have lead to two specific (but non-exclusive) hypotheses with respect to clock models: (i) the latency of the on/off switch from the pacemaker to the accumulator may be more stable for the auditory than for the visual sensory modality and (ii) the rate of the pacemaker for the auditory inputs may run faster than for the visual ones [24], [25], [26].
Candidate causal modeling approaches cited by Morfeld include Robin's G-estimation procedure [ 61, 62] which can be used to estimate the time period between exposures and outcomes such as death, and thus appear promising for incorporating covariates into models of the latency period.
A theoretical model of the latency of these schedulers is developed and used to design experiments targeted at measuring scheduler latency.
Our model recapitulates the latency of tumor formation associated with adult onset HCC.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com