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Hence, it will be interesting to investigate and compare in further studies with animal models the efficacy of inactivated and live-attenuated vaccines to provide protection against infection with the pandemic (H1N1) 2009 virus.
However, as simulated by mathematical models
Using two NOD/SCID mouse models, the efficacy of vorinostat was observed in B cell precursors childhood ALL in vivo.
Similar(57)
Using a mouse model, the efficacy of these arteether lipid formulations against Plasmodium berghei was evaluated.
Strikingly, in the 4T1Ch9 model, the efficacy of either α-4-1BB/MEKi or α-OX-40/MEKi was significantly greater (two-way ANOVA; P < 0.0001) than the combination of α-PD-1 and MEKi (Fig. 7a, b).
We modeled the efficacy of the ICD as a reduction in the relative risk of death on the basis of the hazard ratios reported in the individual clinical trials.
Therefore, in a swine model, the efficacy of CO2 removal at a dialysis flow rate using regional trisodium citrate anticoagulant and also systemic anticoagulant was determined utilizing a modified renal dialysis unit.
On the basis of these results, we chose the underlying distribution for modeling the efficacy of combination vaccines as a normal distribution on the log immune response such that the fold range is 65 on the untransformed responses.
Here we have determined in the DIO mouse model the efficacy of a related small molecule compound, Genz-112638, which is currently being evaluated clinically for the treatment of Gaucher disease, a lysosomal storage disorder.
For example, a study trying to model the efficacy of RNAi experiments is given in [ 28].
Modeling the efficacy of various drugs in combination, however, should consider nonlinear dependencies.
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