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In addition to the elementary processes that are intrinsic to the oscillator models, the additional reaction channels that need to be incorporated when considering miRNA regulation therefore are (1) (2) (3) (4) where m denotes the miRNA, M the mRNA associated with the gene expression and C RISC denotes the RISC complex.
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However, modeling the additional flexibility comes at the expense of further computational complexity.
At least three different models have been proposed: the severity model, the additional deficit model and the component model.
Through the myopic addiction model, the additional variable (lnQt−1) shows no statistical significance.
Had we not radically changed the service model, the additional costs would have been very much greater and no savings would have been realized.
However according to our analysis using the branch model, the additional lys2 gene copies may still be subject to purifying selection (data not shown).
For sensitivity, once early weight gain is included in the prediction model, the additional predictive value of baseline characteristics diminishes and becomes marginal after 3 weeks.
Using this model, the additional risk for lung cancer due to ETS exposure at work can be calculated taking the exposure duration into account.
In infectious disease modeling, the additional consideration of change in host susceptibility (or immune status) that occurs in the context of infection is critical.
The change in the AUC between the base model and the model with the additional risk factor included.
Although many are using iPads, they often are buying less costly models without the additional cost of curriculum software.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com