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As such, this appears to be one of the few murine models that replicates the spectrum of grades and stages observed in human prostate cancer [18].
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We identified 83 SNP-SNP models that replicated across the discovery and replication datasets.
In the UK, most high street stores use models that replicate a size eight or 10 and an impressive height, around 6ft.
One important advance in understanding the pathogenic mechanisms of this disease has been the development of multiple murine models that replicate many of the clinical, neuropathological, and molecular events in HD patients.
Transgenic rodent models that replicate various aspects of PD have been developed.
There are currently no other rodent models that replicate these features of human BO in the setting of fully vascularized aerated lung parenchyma.
Animal models that replicate the complexity of disease mechanisms over time are needed.
There were 22 SNP-SNP models that replicated with an LRT P-value < 0.01 (Fig. 3).
Therefore, alternative models that replicate this complex disease need to be developed (Feldmann et al, 2009; Sharma et al, 2010).
Furthermore, the multifactorial nature of AMD makes the construction of genetically engineered animal models that replicate AMD difficult.
Major obstacles include the lack of availability of good animal models that replicate aspects of the phenotype and tests to assay depression-like behaviour in non-human species.
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