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The presence of ribonuclear foci was also described in three other DM1 fly models that expressed interrupted 240 and 480 CTG expansions (46, 64, 65) (Supplementary Material, Table S3).
Only one model that expressed the HCV core protein developed HCC with high incidence [6], and two models that expressed the HCV core together with E1 and E2 proteins developed HCC with very low incidence [7], [8].
More direct evidence for p53 involvement in longevity came from studies on two mouse models that expressed truncated mutant forms of p53 [ 7, 8].
To develop a model of SCA6, we previously generated several KI mouse models that expressed the mutant transcripts under the control of an endogenous promoter.
We estimated mortality due to influenza using regression models that expressed weekly deaths as the sum of a regular seasonal component of variation, a long-term trend, a contribution from each of the influenza types, a component related to meteorological conditions, and an error term.
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That's certainly the case for Calvin Klein Collection, where the men's creative director, Italo Zucchelli, seeks models that express the American athleticism that has become the label's trademark.
Investigations of pharmacokinetics and safety assessments of drug metabolites are often carried out in dogs, minipigs, marmosets, monkeys, and/or genetically engineered mouse models that express human enzymes.
The models that express these variables as quadratic polynomial functions of the three factors were obtained using the Design of Experiments methodology and the commercial software MODDE 5.0.
FB prediction relies on mathematical models that express the TCP throughput as a function of the characteristics of the underlying network path.
The obtained data were used to develop MPV models that express the performance of an electrophoretic run (measured as peak efficiencies of Q10, AA, and FA) in terms of the MCs and PVs.
Finally, one aim of developing mouse tumor models that express EGFRT790M-driven lung adenocarcinomas is to use them to identify agents that can potentially overcome T790M-mediated resistance.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com