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In tumor and angiogenesis models, surface expression of α v β 3 has been demonstrated to be a strong ligand for targeting endothelial cells in angiogenic vessels [ 63].
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To characterise hFb and hUASMC as model systems, surface expression of TRAIL receptors and TRAIL resistance were evaluated.
We can compare the models to the surface expression of the faults.
Statistical analysis of the dose-dependent modulation of DC surface marker expression levels by bovine IL-10 was performed using a one by one correlation model: surface marker expression level or cytokine concentration = bovine IL-10 concentration.
Genetic depletion of mitochondrial DNA (ρ0 model) increased CD133 cell surface expression in an irreversible manner and yielded a human glioma model in which CD133 is constitutively expressed.
We developed a mouse model in which ICOS surface expression levels are genetically predetermined to test our hypothesis that genetic regulation of ICOS expression controls the severity of Th2 responses in vivo.
In these murine infection models, membrane CD69 interferes with surface expression of sphingosine 1-phosphate receptor 1 and blocks B-cell egress from particular lymphoid organs [34], [35].
However, these models cannot determine if increased ICOS surface expression is contributing to disease progression or alternatively, if it is a result of augmented T cell activation.
Furthermore, surface expression of a model surface protein was monitored by an enzymatic whole-cell assay and flow cytometry.
With the emergence of two monocyte subsets, a multistep model would envision that the relative surface expression of adhesion molecules and chemokine receptors determines the recruitment behaviour of each subset.
Circulating insulin levels dynamically modulate striatal DAT activity, with decreased DA uptake and DAT surface expression seen in animal models of diabetes and after food restriction (FR 20,21.
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