In a XooNIps-based database, digital resources are stored according to their respective categories, e.g., research articles, experimental data, mathematical models, stimulations, each associated with their related metadata.
In an in vitro hypoxia model, stimulation of tubular epithelial cells with SCF activated survival signaling and decreased apoptosis.
On a cellular basis in an experimental cell culture model, stimulation of trigeminal ganglia neurons with potassium chloride, capsaicin or a cocktail of inflammatory mediators used to mimic neurogenic inflammation resulted in an elevated CGRP release in these cells.
In the CIA model, stimulation of DCs with TNFα generates DCs with a strong suppressive capacity.
However, in our model, stimulation of the migratory phenotype was observed without irradiating the cancer cells.
Additionally in a mouse model stimulation with estrogen led to an increase of MMP2 and promoted ectopic implantation of endometrial tissue [ 46].
In our experimental model, stimulation of the lbpva55 cell line with 10 ng/ml IL-1β resulted in upregulation of mRNA and protein expression of collagenases MMP-1 and MMP-13 and the stromelysin MMP-3.
In our model the observed phenomenon of reduction in plasma renin activity emerges as a property of the integrated computational model: stimulation of the baroreflex and associated drop in sympathetic tone is predicted to result in a drop in renin production even with the long-term drop in mean pressure.
Structural identifiability is a theoretical property of the model structure, depending only on the model input (stimulation function) and output (observation function): It is not related to the specific values of the model parameters.
When modeling stimulations, a conductive boundary condition should be used on the surfaces of the electrodes through which a current flows, namely the stimulation and ground electrodes.
