Sentence examples for models significantly sensitized from inspiring English sources

Compared with the nontargeting control, single knockdown of KLF4 or KLF5 in the BT474 and M6 models significantly sensitized the cells to lapatinib treatment.

Interestingly, doxorubicin and docetaxel significantly sensitized both ALDH− and ALDH + cells; however, ALDH− cells were more sensitive to these agents than the ALDH + cells and commercial BCSCs.

(C,D) RR cells significantly sensitized to crizotinib treatment upon β-catenin siRNA knockdown.

Pretreatment of A375 cells with GrB/scFvMEL significantly sensitized melanoma cells to ionizing radiation assessed using a clonogenic survival assay.

Pretreatment of A375M cells with IκBα/scFvMEL significantly sensitized melanoma cells to ionizing radiation assessed using a clonogenic survival assay.

Among we have tested, siRNA-mediated knockdown of ATP1A1 significantly sensitized cells to aurilide B. ATP1A1 encodes the ubiquitously-expressed α-subunit of the Na+/K+ ATPase complex.

In addition to ROC, 28 other rocaglates significantly sensitized these cells to TRAIL – defined as IC50 < 1 µM for growth inhibition in the presence of TRAIL (see Supplementary Fig. S1 for dose-response curves for individual rocaglates).

Sirolimus (10 nmol/L) significantly sensitized the cells to anticancer drugs, leading to decreased IC50 values of ADM, GEM and MTX (from 25.48, 621.41 and 21.72 μmol/L to 4.93, 73.92 and 6.77 μmol/L, respectively).

Moreover, inhibition of HSP90 activity through gene silencing by specific siRNA significantly sensitized Lexa-induced apoptosis.

Apoptosis assays indicated that HSP90 knockdown (Fig. 7F) significantly sensitized Lexa-induced apoptosis in HCC cells (Fig. 7G, and 7H).

Hence, GC7 significantly sensitized bladder cancer cells to doxorubicin.