Overexpression of PDGF-D in a mouse model significantly enhanced prostate carcinoma onset and invasiveness [ 184].
We also showed that incorporating a simplistic ASRV model significantly enhanced the quality of the computer simulation data.
The lower AIC of the probabilistic niche model shows that the added freedom in ni values in this model significantly enhances its ability to reproduce the empirical food web studied here compared to the allometric niche model, which has niche position equal to log of body mass.
In animal models, APS significantly enhanced not only the recovery of platelets, other blood cells and their progenitor cells, but also the formation of Colony Forming Unit (CFU).
Our data showed that inactivation of erbB3 signaling with MM-121 specifically downregulated Survivin in our in vitro models, and significantly enhanced paclitaxel-induced cytotoxicity and apoptosis in the otherwise resistant breast cancer cells.
The in vivo application in a rabbit model proofed significantly enhanced transplant stability and less suture losses comparing PDC and HDC to AM while none of the matrices induced considerable inflammation.
Furthermore, in an intraperitoneal model, masitinib significantly enhanced survival with no indication of general toxicity, as indicated by a lack of weight loss at the administered doses.
Consistent with our model, PhLP1 significantly enhanced forskolin-stimulated AC activity in striatal membranes and produced an approximately three-fold reduction in EC50 for forskolin.
Similar results were generated when recovery rates of bacterial counts were compared for the murine bacteraemia model with significantly enhanced amounts of D32 in comparison with UW7709 isolated from liver, kidneys, spleen and blood.
In three models, iRGD peptide significantly enhanced drug accumulation into tumour.
