When we compared CD3/CD28-induced cell death predicted by the PLSR model to experimental measurements, the model showed robust predictive capability (Fig. 4d; R2Y = 0.96, Q2 = 0.68).
Wind tunnel verification of the model showed robust estimation of surface pressures in complex urban configurations.
Still, the promoter silencing appears to be model or cell type dependent, as tumors in the SCLC model showed robust Luciferase expression judged by the exponential increase in luminescence signals measured in the majority of the invCAG-Luc Rb1 invCAG-Luc Rb1 chimeras (F/F 4B).
Consistent with our results, animal models of glaucoma showed robust activation of pathways mediated by AP-1/c-Fos/c-Jun [ 5, 37, 38], NF- κB [ 39], complement [ 36, 40- 42], androgen receptor [ 39, 43] and ephrins [ 44].
Thus, delta ligands have low analgesic efficacy in acute pain models but show robust analgesia efficacy in a variety of chronic pain conditions accompanied by inflammation [ 16, 17].
Results from the image-based meta-analysis (IBMA) method and mixed effects model with site covariance method both showed robust activation in expected regions (i.e. dorsolateral prefrontal cortex, anterior cingulate cortex, supplementary motor cortex, superior parietal cortex, inferior temporal cortex, cerebellum, thalamus, basal ganglia).
Thus, the yeast model could show robust performance with a balance of amplification, dynamic range, and tracking.
Results of sensitivity analyses of smaller and larger imputation models showed similar results, indicating a robust imputation model.
A study to validate the models showed that model 6 is also robust for the analyzed populations.
Since Poisson models showed data overdispersion, we used more robust negative binomial models for all estimations and allowed for non-linearity of the weekly time term using restricted cubic splines.
