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Also, non-linear models require much more data to be trained then linear models.
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The parameters of modeling require much information; especially the variable S on the right side of equation, will cause a serious complication in the solution process.
Additionally, our model requires much simpler sensing requirements.
Detailed micro-modelling requires much computational effort.
The 3D model requires much higher computational resources as compared to a shell model based on the equivalent approximation.
But, original Craft-Launder-Suga model requires much more computation time if cubic stress-strain relation is implemented.
Therefore, reconciliation of the different levels of divergence at LR and HR with the SIM intrinsic to the 4-parameter model requires much more highly elevated substitution rates along the lineages leading to the island species than are required by allowing different isolation times for the two classes of loci.
Because this model requires much less NMO-IgG than the NMO/EAE models, it is an ideal tool for therapeutic studies such as the initial testing of small molecules to inhibit binding of NMO-IgG to its cellular targets in vivo 57, 58 or of drugs inhibiting neutrophil effector molecules 50.
Although the general use of bootstrap, jackknife, and cross-validation approaches do have the potential, implementation in the mixed-effect modeling will require much more sophistication.
The results of SWAT model revealed that the SWAT model does not require much calibration and can be used in predicting the water balancing components of the study area.
The major advantage of the model is that, unlike other conventional conceptual simulation models, it does not require much calibration (Gosain et al. 2005).
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