Sentence examples for models represent major from inspiring English sources

These models represent major U species in natural waters and complexes on bacterial surfaces.

In practice, rigorous validation of models represents major difficulties [ 86, 87], since the very purpose of modelling is to obtain estimates of conditions beyond the available observational data (including into the future): some degree of extrapolation into the unknown is therefore inevitable.

However, data requirements, particularly for the more complex urban models, represent a major obstacle to their employment.

Genetically engineered mouse models represent a major advance in cancer research that allows for the study of gene function in vivo and for the creation of models that more accurately recapitulate human cancers.

These models represent the major breast cancer subtypes found in humans, including triple-negative, basal-type lesions lacking BRCA1, HER2/ERBB2-positive tumors, as well as ERα-negative and ERα-positive, luminal-type cancers that originate in mice expressing mutant PTEN and prolactin in the mammary gland.

8 Achieving such a model of care in most specialist oncology services and evaluating its effectiveness represent major challenges.

These represent major insights, not minor ones.

Individually these represent major public health priorities.

In this study we have chosen model organisms representing major evolutionary splits — the emergence of Chromalveolata (a proposed super-kingdom of plastid-containing eukaryotes [ 36]), Alveolata (the kingdom comprising ciliates, dinoflagellates and apicomplexans [ 37]), and Apicomplexa — to illuminate the origin and divergence of the major ePK groups.

First, regarding the transformation of disputes, the aforementioned "process model" and "meaning model" represent two major pathways within existing studies.

The health states in our model represent the major clinical end points in randomised controlled trials, and correspond to previous cost utility analyses (Kattan et al, 1996; Liberato et al, 1997).