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These models replicate many of the known salient features of human bladder cancer.
While these models replicate many aspects of human RA, none of them mimic the disease completely.
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This model replicates many respiratory features of humans and consequently may be a useful tool to investigate new strategies to treat respiratory disease in influenza-infected infants.
The model replicates many of the features of human disease, with C. difficile toxin-mediated inflammation of the gastrointestinal (GI) tract resulting in histopathological changes in the tissue comparable to those observed in humans (11).
While the murine model replicates many facets of the human immune response [ 9], mice do not show well-formed granulomas and lack the caseous, necrotic centers characteristic of human infection [ 10].
One important advance in understanding the pathogenic mechanisms of this disease has been the development of multiple murine models that replicate many of the clinical, neuropathological, and molecular events in HD patients.
We took the unique opportunity to analyze dynamic inflammatory, renal hemodynamic, and microvascular changes in two clinically relevant large-animal models that replicate many of the biologic features of human septic shock, including the integration of standard day-to-day care resuscitative measures.
That said, we take the fact that the partial equilibrium version of the model passes our more rigorous test as very convincing evidence in favor of using the model for British Columbia (but not for New Brunswick), as the model can replicate many of the outcomes produced by a social experiment without the use of the variation introduced by the social experiment.
We note that though mouse and macaque are not known natural hosts for influenza, they are well-understood model systems that replicate many features of pathogenesis in other hosts.
The model was able to replicate many of the integral features of whole-body cholesterol balance and displays qualitative behaviour similar to that observed in experimental studies [ 52].
Murine models do not equate to pre-eclampsia in women, but they can replicate many of the pre-eclampsia symptoms.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com