None of these two mouse models reflects human AD pathology because none showed significant neurofibrillary tangle pathology and both overexpressed a transgenic construct made to produce large amounts of Aβ [ 16, 20].
The generation of an amenable model reflecting human conditions has been complex.
The aim of this study is to advance a peritoneal injury animal model reflecting human histopathology in order to elucidate the mechanism of progression of peritoneal injury.
McOwan is interested in optical illusions because if his mathematical models of vision can predict new ones, it's a useful indicator that the model is reflecting human vision accurately.
The P. yoelii pre-erythrocytic infection of the mouse represents an accepted model closely reflecting human malaria (Luke and Hoffman, 2003).
Screening for factors relevant to arthritis can be performed in tissue-engineered 3D models reflecting the human environment.
However, most of the available simulation systems rely on rather simple pedestrian navigation models, which reflect human behaviour only in a limited manner.
GDP-induced peritoneal injury models may reflect human PD.
Although the affected primary organs (that is, skin and liver) have not been investigated, the authors of that study concluded that mouse models poorly reflect human inflammatory disease.
