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Nonetheless, the resulting trained models recapitulate some important behaviors.
The inoculated colorectal cancer models recapitulate some features of colorectal cancer metastasis and are useful models for anti-metastatic drug evaluation.
These animal models recapitulate some but not all the typical histologic alterations such as amyloidosis, synapse and neuron loss, tau hyperphosphorylation and inflammation.
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Abca4−/− mice (3), the only STGD1 animal model, recapitulate some of the features of the human retinal disease including abnormal lipofuscin accumulation in the RPE.
This mouse model recapitulates some of the disease and tissue tropism features of ZIKV and has been used to assess other ZIKV vaccine constructs40,41,42.
It is highly unlikely that any cellular model can completely recapitulate such a complex multidimensional process, however the CMP model recapitulates some of the correlated facets of the physiological and pathophysiological aging process in experimental animals and humans.
This model recapitulates some of the features observed in human WHIM syndrome, and allows in vivo observations to be made that are not possible in other systems.
Our network models also recapitulate some of the known TF-target relations, as confirmed by the literature.
Mouse models that recapitulate some features of SS have been used to study the pathogenesis, including the IL-2 receptor alpha chain (CD25) knockout (KO) [ 6, 7].
A number of human progeroid syndromes (Werner, Cockayne, Hutchinson-Gilford, trichothyodystrophy, dyskeratosis congenita, ataxia-telangiectasia) and mutant mouse models (below) recapitulate some aspects of normal ageing and in many instances produce extreme examples of these disorders (Hasty et al, 2003; Kipling et al, 2004; Lombard et al, 2005).
Given the three distinctive subgroups of mouse HCC models, we sought to examine how well these models recapitulate human HCC phenotypes as defined by gene expression patterns.
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CEO of Professional Science Editing for Scientists @ prosciediting.com