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For this reason, and because of the ease of use and reproducibility that can be achieved, these imagable models provide ideal systems for determining anti-metastatic effects of cancer drugs and therapeutic regimens and is well suited for investigating the molecular, cellular and pathologic basis for metastasis to specific organs and tissues.
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These models will provide ideal platforms for investigating the interactions between macro- and microcirculation and the effects of various resuscitation targets and techniques on tissue homeostasis.
Our findings support earlier suggestions of an epigenetic impact of chromatin and chromosomal changes in ICF syndrome and present an example of how human diseases can provide ideal model systems to investigate the functional significance of nuclear architecture.
We propose the mouse models provide an ideal experimental system for further investigation of the early diagnostic and therapeutic potential of 5-ALA-stimulated PpIX accumulation in human breast cancer patients.
Semiconductor nanomaterials in one-dimensional morphology provide ideal models to study the relationship between electrical transport, optical, and other properties with dimensionality and size confinement [11 13].
Multi-domain proteins provide ideal models to study the problem above since many of them consist of more than one domains evolved from the same ancestor and have similar structural symmetry but different sequence symmetry.
The conserved stress conditions thus provide ideal models for studying divergence and evolvability of gene regulation in evolutionarily distant organisms.
Insects and other arthropods provide ideal model systems to study how intraspecific behavioral variation affects phenomena in ecology.
Such species would provide ideal biological models to monitor the biological signatures of an ORD-driven progression over short distances.
Non-human primates (NHPs) and humans share major biological mechanisms, functions, and responses due to their close evolutionary relationship and, as such, provide ideal animal models to study human diseases.
Pigs provide ideal animal models, as porcine studies have been shown to be in general more predictive of therapeutic treatments in humans than rodents [ 11], and pigs are also less expensive and ethically more acceptable than canines and non-human primates.
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