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All models pass the standard testing procedures, which are reported in Table 5 and described in more detail in the Methods section.
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All models passed the Hosmer Lemeshow goodness-of-fit test.
In the final phase of testing, the decontamination efficacy of the steam bag was determined in triplicate for the FFR models passing the phase 2 evaluation using both brands of bags.
In phase 2 testing, FFR models passing the preliminary assessment were evaluated for filtration efficiency following three cycles of steam bag sterilization which included a 30 min drying period between treatments.
Unfortunately, none of these models passed the HL test.
Both models passed the goodness of fit test at alpha = .05.05
All reported models passed the Hosmer-Lemeshow's goodness of fit test.
These models passed the proportional hazards assumption test adhering to the methodology suggested by Lin et al, 31 which is based on cumulative sums of Martingale residuals.
The results show that the proposed models using linear and nonlinear models passed the proposed statistical criteria in the literature, and they are robust and valid for external prediction.
With regard to breast density, although the Gail and Chen models passed the calibration tests, the Gail model overestimated the number of cases in women with breast densities 1 and 2 and the Chen model in women with breast density 4. (1 1: Almost entirely fat, 2: Scattered fibroglandular densities, 3: Heterogeneously dense, 4: Extremely dense.
Sample autocorrelation of residuals are within the bounds of 95% confidence interval with no significant autocorrelation between residuals at different lag times, and the models passed the Box-Ljung test (p = 0.63) on auto-correlation of the final residuals and Kolmogorov-Smirnov test for normality (p = 0.58).
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