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I am also keen to change from zebrafish to mouse models or humans.
McaP has also been considered as a potential vaccine target [56] although its immunogenic potential in animal models or humans is not clear.
The results are not transferable to other animal models or humans with lungs characterized by different pressure-volume-relationships.
Indeed, the possible relation between neurodegeneration and obesity in animal models or humans has been studied now for several decades.
Previous measurements of resting calcium levels in myofibers from dystrophic animal models or humans produced equivocal results.
Recently, several investigators used F-FLT PET to evaluate treatment responses in animal models or humans following molecular targeted therapy [ 22, 42].
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The EPR effect can be visualized in vivo tumor models or human tumors [99, 108].
Other researchers have previously examined the effect of CVVH using several hemofiltration settings in animal models or human clinical study [19 21, 33 35].
At the same time, relatively few genes have reached genome wide significance in anxiety disorders, and there is relatively little work on how exposure to an adverse environment impacts on gene expression in either animal models or human clinical populations.
In this issue of Cell, Palmer and Sorger present data suggesting that cell culture results indicative of synergistic anticancer drug interactions rarely translate clinically and that the results of combination therapies in mouse models or human clinical trials, even if successful, are best explained by the independent activities of the individually administered drugs.
In summary, REGGED represents a resource for the glomerular research community to interrogate genes identified by in vitro systems, rodent models, or human genetic screens for their enrichment in the glomerular compartment.
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