Sentence examples for models of wound from inspiring English sources

Physiologically relevant models of wound healing are essential for understanding the biology of connective tissue repair and healing.

The free radical-scavenging property of UA2 likely contributes to its beneficial effects in the in vivo and cell culture models of wound healing.

Several other transcriptional changes in SKO mice parallel other models of wound healing and dermatitis including elevated expression of tenascin C (Tnc) [27], osteopontin (Spp1) [28], thrombospondin-1 (Thbs1) [29] and Socs3 [30] (Table 7).

Two models of wound contraction have been proposed to explain how tension is generated, both of which rely on cell ECM interactions.

Studying haemocytes in Drosophila models of wound healing can therefore be used to model some aspects of the immune cell responses that occur in mammalian wound healing.

It is an important structural component of interstitial and connective tissues, making it particularly relevant to models of wound healing and fibrosis.

One explanation may be the relative lack of cell death at excisional wound sites (Hopkinson-Woolley et al., 1994; Spurlin and Lwigale, 2013), whereas dead cells and macrophages containing dead cells are observed in zebrafish models of wounding (Li et al., 2012).

We then tested the therapeutic potential of UA2 in a mouse model of wound healing and found that, indeed, topical application of UA greatly accelerated wound healing and enhanced the restoration of normal dermal and epidermal tissue structure in the wound area.

We used three-dimensional tissues as a platform to test the consequences of targeting β4 with these antibodies, which are specific to human β4, first in a static three-dimensional tissue model of non-wounded human epithelium and second in a dynamic three-dimensional tissue model of wound healing.

This shows that the rates of cell motility and proliferation associated with different initial wound shapes are approximately the same, implying that the differences in the closure rates are consistent with a typical mathematical model of wound healing.

Interestingly, the round fibroblast-populated collagen matrix has been used as a model of wound contraction, even though contraction in this model is mostly symmetrical.