Sentence examples for models of toxicity from inspiring English sources

Other approaches to sorting gene expression data for toxicogenomics have included several "unsupervised" methods, in which modeling programs search for patterns within data and generate models of toxicity without being given any hint as to what kinds of expression patterns the researchers expect to find.

In vivo and in silico models of toxicity were combined to test the contribution of individual mechanisms and reveal the multi-modal role played by the cardiotonic and scavenging actions of the triglyceride suspension.

Numerous studies have demonstrated that resveratrol show potent protective effects in various models of toxicity [13], [16], [20] including toxicity induced by NO releasing SNP [16].

However, the presence of EAST-1 in EAEC 17-2, a strain which did not cause diarrhea in volunteers, suggests that EAST-1 is not the sole mediator of diarrhea, an observation confirmed by studies which demonstrated EAST-1 from EAEC 17-2 had identical activities to EAST-1 derived from EAEC 042 in in vitro models of toxicity [7], [97].

Traditional models of toxicity have relied on dissecting chemical action into pharmacokinetic and pharmacodynamic processes.

We obtained these novel observations using fresh DEE and inhalation exposures of previously characterized models of toxicity.

Risk assessment of fluctuating concentrations requires assessment of toxicity over time (prediction of toxic effects beyond test conditions), and such a prediction requires a mechanistic model of toxicity.

Based on this preliminary data, we are able to construct roughly a theoretical predictive model of toxicity based on network response.

These findings led us to propose a two-stage model of toxicity.

However, at this model of toxicity silymarin had better cytoprotective effects compared to saponarin.

Further, toxicokinetic rate constant models were parametrized for each compound to facilitate process-based modeling of toxicity.